Exercise Has a Surprising Benefit

We have long known that exercise is important for many aspects of health. Now researchers at the University of California, San Francisco (UCSF) have identified an even more surprising way it benefits health. They found prostate health impacts nearly 200 genes and expression of 184 of those genes in the prostate gland is linked to vigorous exercise.

The researchers studied the activity of some 20,000 genes in healthy prostate tissue biopsied from several dozen patients. They found 109 genes were “up-regulated” and 75 were “down-regulated” among the men who exercised vigorously for at least three hours a week compared to those who exercised less. Among the genes that exhibited greater expression were a number that already are thought to help thwart cancer progression, including the well-known “tumor suppressor” genes BRCA1 and BRCA2, as well as genes involved in cell cycle and DNA repair.

These genetic findings are indeed powerful. Combined with the already known benefits of exercise for supporting healthy testosterone and weight management, along with minimizing excess insulin and aromatase activity, there’s no question that all men need to keep their bodies in motion. Aim for at least three to four hours of exercise weekly.


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